Use of smokeless tobacco and risk of myocardial infarction and stroke: systematic review with meta-analysis
Boffetta and Straif in their study looked at whether people who utilized smokeless tobacco products were at an increased risk of having myocardia infarctions and strokes. The design of their study was a meta-analysis of studies from Sweden and the United States and the data utilized in their study was obtained from electronic databases and references lists. The results of their study showed that both in the United States and Sweden individuals who used smokeless tobacco products had a higher risk of death from myocardial infarction and stroke. They suggest that more research needs to be conducted that helps identify the specific ingredients in smokeless tobacco products that cause deaths from cardiovascular disease.